Toolbox: Treating Latent Tuberculosis Infection in High-Risk Populations

Welcome to the LTBI Toolbox. These tools are primarily for urban TB programs wishing to improve secondary prevention of TB in those groups at high risk of progression to TB disease, including the homeless, chemically dependent, and mentally ill. The materials include sample letters, forms, and job descriptions and protocols as well as templates of these tools for adaptation to local programs.

Using this toolbox will enable you to:

  • Understand the background and rationale for Directly Observed Therapy (DOT) in the treatment of Latent TB Infection (LTBI)
  • Learn about the San Francisco TB Outreach and Prevention Program and other successful models
  • Outline the essential components for a successful program with high completion rates
  • Build a DOT team
  • Build community collaboration

Print Instructions
The toolbox is designed to be used on-line or from a Compact Disc (CD). Working with the toolbox on your screen will let you easily move from text to associated tools and back again. However, if you want to make a printed copy, you can do so by following these steps:

1) Print this page as a coversheet.

2) Print the site map as an index. Click on site map at the left hand side of this page. Then either print the page or highlight and copy the site map into a word processing program before printing.

3) Print the file below, which contains all of the text sections in sequential order.

4) Print each of the tool files - tool files must be opened and printed individually from the Tools folder on the left side of the screen - then order them by the site map list.
The entire Text portion of the Toolbox is also available for you to download and print.
Some of our text and tools are in PDF format which requires an Adobe Acrobat Reader to open. Install a free copy of the Adobe Reader if your system does not have one.

Please note:  This toolbox contains information about the treatment of latent tuberculosis infection (LTBI). It was produced prior to the release of updated guidelines from the CDC in February 2020.  For the most current guidance available regarding LTBI treatment, please see: Guidelines for the Treatment of Latent Tuberculosis Infection: Recommendations from the National Tuberculosis Controllers Association and CDC, 2020

Date of Release:  January 2005